Pronuclear Transfer Technology
Question
In the context of recent advances in human reproductive technology, "Pronuclear Transfer" is used for
Options
fertilization of egg in vitro by the donor sperm
genetic modification of sperm producing cells
development of stem cells into functional embryos
prevention of mitochondrial diseases in offspring
Explanation
Pronuclear transfer is an IVF technique designed to prevent the inheritance of mitochondrial diseases. It involves the transfer of pronuclei from a fertilized egg with defective mitochondria into a healthy, enucleated donor egg. The resulting embryo has nuclear DNA from the parents and healthy mitochondrial DNA from the donor (resulting in a 'three-parent baby'). > One-line conceptual takeaway: Pronuclear transfer replaces defective mitochondrial DNA to stop hereditary mitochondrial diseases. Answer: (d).
Question details
Year
2020
Paper
GS Paper 1
Question
Q37
Subject
Science & Technology
Sub-topic
Biotechnology & Genetics
Type
Factual single
Difficulty
Medium
Nature
Current-affairs-linked
Source hint
Three-parent baby news (UK regulatory approval)
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