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Q37·GS Paper 1 · Prelims 2020

Pronuclear Transfer Technology

S&TBiotechnology & GeneticsFactual singleMediumCurrent-affairs-linked

Question

In the context of recent advances in human reproductive technology, "Pronuclear Transfer" is used for

Options

a

fertilization of egg in vitro by the donor sperm

b

genetic modification of sperm producing cells

c

development of stem cells into functional embryos

d

prevention of mitochondrial diseases in offspring

Answer

Explanation

Pronuclear transfer is an IVF technique designed to prevent the inheritance of mitochondrial diseases. It involves the transfer of pronuclei from a fertilized egg with defective mitochondria into a healthy, enucleated donor egg. The resulting embryo has nuclear DNA from the parents and healthy mitochondrial DNA from the donor (resulting in a 'three-parent baby'). > One-line conceptual takeaway: Pronuclear transfer replaces defective mitochondrial DNA to stop hereditary mitochondrial diseases. Answer: (d).

Question details

Year

2020

Paper

GS Paper 1

Question

Q37

Subject

Science & Technology

Sub-topic

Biotechnology & Genetics

Type

Factual single

Difficulty

Medium

Nature

Current-affairs-linked

Source hint

Three-parent baby news (UK regulatory approval)

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